CRYOSURGERY
with LIQUID NITROGEN
C-2000 A PROVEN & TESTED
LIQUID
NITROGEN CRYOSURGICAL SYSTEM WITH INTEGRATED TISSUE TEMPERATURE
INDICATOR:
cotton application
are poor heat sinks.
depth of necrosis with this method usually will
not exceed 1.5mm [LN2.with swab only -20°c]
Enhanced Surgical Results--Precisely
monitoring tissue temperature through the use
of thermocouple needles and needle depth templates. |
NEW INDICATIONS
FOR CRYOSURGERY IN INFECTED PATIENTS:
Cryosurgery
is a relatively risk-free bloodless therapy which
may be used in a variety of conditions and tumors,
in high-risk patients, for physicians who are
dealing with a large population with AIDS and
hepatitis, cryosurgery is now becoming a safe
alternative to other procedures where more exposure
would be anticipated.
Cryosurgery is particularly recommended for patients
considered to be poor surgical candidates (e.g.
children. the elderly, patients with cardiopulmonary
or those who have a variety of bleeding disorders).
Cryosurgery can also be used in patients who have
radiation damage and is particularly advantageous
in the treatment of multiple lesions in a single
visit. patients taking anticoagulant, those with
previous history of poor wound healing after standard
surgical procedures, and those with fair skin
are often the best candidates for Cryosurgery.
Patients with multiple large lesions are also
excellent candidates, while those with many small
(1-2mm) lesions are often best treated with other
techniques. Cryotheraphy is the preferred modality
in the treatment of warts and molluscum contagiosum
in persons infected with the HIV. |
FULL-FACE CRYO-PEEL TERMED HIGHLY EFFECTIVE IN TREATMENT
OF SUN DAMAGED SKIN:
Full-face liquid nitrogen
cryo spraying is a "highly effective way
of treating large
areas of actinic keratosis and sun damaged skin
and burnt skin" |
KEY FEATURES:
- Adjustable pressure control
resulting in variable flow control
- Wide selection of interchangeable tips
- Tissue temperature monitor [optional]
- Thermocouple needles [optional]
- Needle depth templates [optional]
- Semi-portable with low-electric (50 to 110V)
before set in motion for procedure. |
SPECIFICATION:
| Capacity |
Length |
Width |
Net Weight |
nstrument
Weight |
Weight
With
package |
MAXI
(0.7 Litre) |
36 cm |
7.5 cm |
650 gr |
820 gr |
3220 gr |
MINI
(0.5 Litre) |
29 cm |
7.5 cm |
555 gr |
730 gr |
3120 gr |
|
CRYOSURGERY ... OVER 96% EFECTIVE IN TREATMENT
OF SKIN CANCER AND CUTANEOUS DISORDERS:
Over 96% success rates using
liquid nitrogen for treating head and neck tumors.
Knowledge of the TEMPERATURE in the tissue in
the treatment of any cancer is critical to success
of therapy.
Surface temperature
reductions attainable with various refrigerant. |
| Refrigerant |
Temperature
(°C) |
| Ice |
0 |
| Salt-Ice |
-20 |
| CO2 Snow |
-76 |
| Co2 Slush |
-20 |
| Nitrous
oxide |
-89 |
| Liquid nitrogen
(LN2) |
-20(swab)
-150 (probe) & -196 (spray) |
|
|
TABLE 3 . TREATMENT PARAMETERS FOR CRYOSURGERY
| Lesion Type |
Treatment |
Tip |
Time (sec) |
Target (mm) |
Technique |
Thermocouple
Required |
Result |
| Hypertrophic
actinic keratosis |
 |
choice |
| |
Alternate |
| |
Adjunct |
|
B |
F=20-30
T=30-40 |
2 |
Cryospray
Cryoprobe
Cryocycle |
No |
Excellent to
good |
| Seborrheic
keratosis |
| |
choice |
|
Alternate |
|
Adjunct |
|
B |
F=10-30
T=20-30 |
2.5 |
Cryospray
Cryoprobe
Cryocycle |
No |
Good to fair
|
| Dermatofibroma |
|
choice |
|
Alternate |
| |
Adjunct |
|
Probe |
F=20-30
T=30-40 |
3-4 |
Cryospray
Cryoprobe
Cryocycle |
No |
Good to fair
|
| Basal
cell carcinoma |
|
choice |
|
Alternate |
| |
Adjunct |
|
A(>1cm)
B(<1cm) |
F=60-120
T=60-180 |
3-4 |
Cryospray
Cryoprobe
Cryocycle |
Yes |
Good to fair
|
| Lentigo
maligna |
|
choice |
| |
Alternate |
| |
Adjunct |
|
A or B |
F=60-120 |
3-4 |
Cryospray
Cryoprobe
Cryocycle |
Yes |
Excellent to
good |
|
F: freeze time |
T: thaw time |
|
:
Preferred technique treatment |
BENIGN LESIONS TREATED WITH CRYOSURGERY C-2000T (TABLE
1-1)
Acne rosacea-Acne vulgaris-Angiokeratoma
of Fordyce- Angiokeratoma, solitary type-Angiolymphoid
hyperplasia- Dermatofibroma Angioma, cherry and
spider- Keratoacanthoma Chondrodermatitis choronicus
helicus- Disseminated superficial actinic porokaratosis-
Epidermal nevus-Hidradenitis supparativa- Granuloma
faciale- Granuloma fissuratum- Keloid- Leishmaniasis-
Lichen simplex chronicus- Lentigines (simplex
or solar types)- Mucocele- Lichen planus- Lichen
sclerosus et atrophicus- Molluscum contagiosum-
Prokeratosis of Mibelli- Myxoid cyst- Prokeratosis
plantaris discreta- Prurigo nodularis- Psoriatic
plaques- Pyogenic granuloma- Sebaceous hyperplasia-
Seborrheic keratosis- Steatocytoma multiplex-
Syringoma- Trichiasis- Venous lake- Verrucae-
Condyloma acuminatum- Periungual Verrucae- Verruca
plana- Verruca palmaris and plantaris- Verruca
vulgaris. |
a. Extensive noduloulcerative BCC at nasolabial crease and melolabial
fold in an 85-year-old man.
|
 |
b. Cryosurgery of entire lesion with open - spray technique.
Note extension and treatment to nasal sill. |
 |
c. Exudation and sloughing 1 week
postoperatively. |
 |
d. Drying and healing of treated site 2
weeks postoperatively |
 |
e. Continued healing with crusting 3
weeks postoperatively. |
 |
f. Excellent results 1.5 years after treatment. |
 |
MALIGNANT LESIONS TREATED WITH CRYOSURGERY C-2000T
(TABLE 1-2)
Basal cell carcinoma
Bowen's disease (carcinoma in situ)
Kaposi,s sarcoma (in AIDs)
Metastatic melanoma (palliative treatment)
Squamous cell carcinoma
Actinic keratosis with squamous cell carcinoma
Adenoid type
De novo type |
PRECANCEROUS LESIONS OR TUMORS OF UNCERTAIN BEHAVIOR
TREATED WITH C-2000T (TABLE 1-3)
Actinic cheilitis
Actinic keratosis
Bowenoid papulosis
Keratoacanthoma
Lentigo maligna
Leukoplakia |
APROXIMATE FREEZE TIMES FOR COMMON BENIGN LESIONS
(TABLE 2-1)
| Lesions |
Freeze
time (seconds) |
| Verruca plana |
5 |
| Lentigo |
7 |
| Sebaceous adenoma |
5-10 |
| Actinic keratosis |
5-10 |
| Verruca vulgaris
|
15-20 |
| Prurigo nodularis |
30 |
| Keloid |
30 |
| Hemangioma |
60+ |
| Keratoacanthoma |
30 |
| Dermatofibroma |
60+ |
| Granuloma faciate
|
30 |
| Granulma annulare |
20 |
| Chondrodermatitis
|
30 |
| Psoriasis plaque |
15-30 |
| Cherry angioma |
10 |
| Nevus |
10 |
| Leukoplakia |
15 |
| Mucocele |
30 |
| Mulluscum contagiosum |
5-10 |
| Seborrheic keratosis |
10-15 |
CURE RATES OF PRIMARY TUMORS ACCORDING
TO SIZE (IN CENTIMTERS) TABLE 3-1
| . |
0-0.5 |
0.6-1.2 |
1.3-2.4 |
2.4+ |
|
| Basal cell carcinoma |
97.6% |
97.1% |
94.1% |
97.8% |
|
| Number of cases treated |
834 |
1218 |
373 |
92 |
|
| Squamous cell carcinoma |
96.4% |
97.8% |
96.5% |
100% |
|
| Number of cases treated |
139 |
313 |
86 |
17 |
|
CRYOSURGERY FOR BENIGN, PREMALIGNANT, AND MALIGNANT LESIONS
TABLE 3-2 . CURE RATES FOR TREATMENT OF
PRIMARY TUMORS ACCORDING TO CRYOSURGICAL TECHNIQUE
| Refrigerant |
Shave & Freeze |
Curettage & Freeze |
Single Freeze |
Double Freeze |
Curettage & double Freeze |
Shave & Double Freeze |
| Basal cell carcinoma |
100% |
97.7% |
95.8% |
96.3% |
98.4% |
100% |
| Number of cases treated |
56 |
731 |
566 |
711 |
788 |
83 |
| Number recurrent |
0 |
17 |
24 |
26 |
13 |
0 |
| Percent recurrent |
0 |
2.3 |
4.2 |
3.7 |
1.6 |
0 |
| Squamous cell carcinoma |
100% |
97.6% |
97.9% |
95.1% |
100% |
100% |
| Number of cases treated |
32 |
211 |
144 |
143 |
105 |
23 |
| Number recurrent |
0 |
5 |
3 |
7 |
0 |
0 |
| Percent recurrent |
0 |
2.4 |
2.1 |
4.9 |
0 |
0 |
TABLE 3-3 . CURE RATE ACCORDING TO TUMOR SITE
| |
Basal Cell Carcinoma |
Squamous Cell Carcinoma |
| Location |
No.
Recurrent |
No.
Treated |
(%)
Recurrent |
(%)
Cure Rate |
No.
Recurrent |
No.
Treated |
(%)
Recurrent |
(%)
Cure Rate |
| Ear |
4 |
198 |
2.0 |
98.0 |
1 |
85 |
1.2 |
98.8 |
| Nose |
29 |
728 |
4.0 |
96.0 |
5 |
53 |
9.4 |
90.6 |
| Eyelids |
1 |
24 |
4.2 |
95.8 |
1 |
4 |
2.5 |
75.0 |
| Nasolabial fold |
3 |
51 |
5.9 |
94.1 |
0 |
2 |
0 |
100.0 |
| Other face |
28 |
984 |
2.8 |
97.2 |
5 |
234 |
2.1 |
97.9 |
| Trunk |
2 |
354 |
0.6 |
99.4 |
1 |
17 |
5.9 |
94.1 |
| Arm |
2 |
133 |
1.5 |
98.5 |
1 |
156 |
0.6 |
99.4 |
| Legs |
0 |
33 |
0 |
100.0 |
0 |
11 |
0 |
100.0 |
| lips |
3 |
44 |
6.8 |
93.2 |
0 |
21 |
0 |
100.0 |
| Scalp |
2 |
42 |
4.8 |
95.2 |
1 |
11 |
9.1 |
90.9 |
| Neck |
2 |
158 |
1.3 |
98.7 |
0 |
44 |
0 |
100.0 |
| other areas |
5 |
295 |
1.7 |
98.3 |
0 |
39 |
0 |
100.0 |
| Total |
81 |
3944 |
2.7 * |
97.3 ‡ |
15 |
677 |
2.2 * |
97.8 ‡ |
* Average recurrence rate.
‡ Average cure rate
TABLE 3-4 . CURE RATES OF PRIMARY TUMORS BY DATE
OF TREATMENT:
| |
1968-70 |
1971-75 |
1976-80 |
1981-85 |
1985+ |
Total |
| Basal cell carcinoma |
95.3% |
94.5% |
96.3% |
98.0% |
99.4% |
96.9% |
| No. treated |
236 |
438 |
779 |
712 |
469 |
2634 |
| Squamous cell carcinoma |
91.2% |
98.3% |
98.3% |
97.5% |
98.5% |
97.3% |
| No. treated |
68 |
117 |
230 |
80 |
68 |
563 |
ACCESSORIES of C-2000 T.B.T
Different kinds and shapes
of probes for treatment of various lesions.
Ball probes, conical probes, concave probes, flat
probes, cervical probes, hemorrhoid probes, mini
probes, sharp-pointed probes, Palate probes (all
optional) and standard probes.
|
NOTICE: All probes are chemically
disinfected with CIDEX or HABITANE.
The company reserves the
right to make changes in the specification at any time
without notice.
Bent spray
extension (#103):
Used to reach condylomata in the perianal,
rectal or vaginal areas, hyperplastic lesions
or lesions which are generally difficult to
reach.
|
|
Intra-
nasal bayonet:
Straight spray (#105-S), left spray (#105-L)
and right spray (#105-R). Used to treat turbinates. |
|
Straight
spray extension (#106):
Used to reach condylomata in the perianal, rectal
or vaginal areas, hyperplastic lesions or lesions
which are generally difficult to reach. |
 |
Delrin
accessory stand (#311):
A Stand to hold up to 8 apertures or probes. |
 |
Cryochambers:
6mm (#104-6)
10mm (#104-10)
15mm (#104-18)
18mm (#104-18)
31mm (#104-31)
Permited profound and precise surgical destruction
of tissue by allowing a confined spray of liquid
nitrogen to pool continuously over deep lesions.
Used to treat large warts and deep tumors. |
 |
Cryoplate
(#303):
A transparant lexan plate with 4 various sized
conical openings. Used to concentrate spray
within a limited area. |
 |
Cryocones
(#304):
Set of six varied neoprene cones used to concentrate
spray within a limited area. |
 |
|
CONTACT TIPS FOR PROCTOLOGY |
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|
CONTACT TIPS FOR OPHTALMOLOGY |
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|
LONG SPRAY PROBES FOR DERMATOLOGY |
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| SPRAY PROBES FOR DERMATOLOGY
|
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|
CONTACT PROBES FOR DERMATOLOGY |
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